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Recently a reciprocal fusion between YPEL yippee like and PP
2019-06-13
Recently, a reciprocal fusion between YPEL5 (yippee-like 5) and PPP1CB (serine/threonine protein phosphatase-1 beta catalytic subunit) was described to be exclusively expressed in more than 90% of primary CLL samples [5] and not in control samples or samples from patients with other hematological ma
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Another key challenge requires special attention in
2019-06-12
Another key challenge requires special attention in improving maternal health in western China. On the basis of recent estimates, China has more than 250 million so-called rural-to-urban migrants who move from the countryside to cities to seek better paid jobs. A substantial number of these people c
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Although high and variable frequencies of sickle cell trait
2019-06-12
Although high and variable frequencies of sickle cell trait in different ethnic groups in Uganda have been reported previously, those data were from around 70 years ago and were based on small sample sizes. Thus, the findings of Ndeezi and colleagues provide a contemporary overview that is nationall
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By showing the great variability in surgical
2019-06-12
By showing the great variability in surgical outcomes across LMICs, Uribe-Leitz and colleagues have shared with the world instructive knowledge that aids our ongoing advocacy efforts to promote quality in surgical care in resource-limited settings. Ultimately, for destitute sick and injured patients
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Atrial fibrosis is one of the fundamental mechanisms
2019-06-12
Atrial fibrosis is one of the fundamental mechanisms for the pathogenesis of atrial fibrillation (AF), but the underlying electrophysiological changes involved are not completely understood. Aging, neurohumoral activation, and chronic atrial stretch due to structural heart disease activate various s
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br Case report The patient then achieved disease free
2019-06-12
Case report The patient then achieved disease-free status as noted in a series of routine image studies during regular follow-up at our oncology clinic. In November 2011, she presented due to hematuria for several days. Diagnostic cystoscopy showed a mass lesion on the urinary bladder. Whole body
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br Conflict of interest br Acknowledgments This study
2019-06-12
Conflict of interest Acknowledgments This study was supported by the National Natural Science Foundation of China (Nos. 81273501 and 81470378). Introduction Sudden cardiac death (SCD) is a tragic event and the aftermath is devastating to the surviving family and community. SCD occurs in ne
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Estas ideas permanecieron vigentes durante mucho tiempo ante
2019-06-12
Estas ideas permanecieron vigentes durante mucho tiempo antes de la revolución científica desatada por el racionalismo. Un ejemplo es cómo las nociones neumáticas —derivadas de la idea de que el mundo fue creado por un soplo divino— todavía son palpables en el Primero sueño de sor Juana cuando inici
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Sierra Leone Liberia and Guinea were among the
2019-06-12
Sierra Leone, Liberia, and Guinea were among the worst places to be a mother before the Ebola crisis. However, substantial progress had been made in recent years in terms of maternal mortality order AMN-107 and increased access to maternal and reproductive health care, resulting in 50% of deliverie
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La embajada argentina en Guatemala
2019-06-12
La embajada argentina en Guatemala consideraba que, FMK diferencia de El Salvador, el ejército guatemalteco y las fuerzas armadas en general mantenían una cohesión firme contra el comunismo. Esta certeza calmaba más las ansiedades que las cordiales relaciones mantenidas con el anticomunista Mario Sa
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br Study limitations br Introduction The
2019-06-11
Study limitations Introduction The spread of basic life support (BLS), including use of automated external defibrillators in the general public, may increase the chance of survival from sudden cardiac death (SCD). Survivors usually have underlying cardiac diseases, such as coronary artery dise
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mitoxantrone Current ASCO recommendations suggest initiating
2019-06-11
Current ASCO recommendations suggest initiating bisphosphonate therapy in myeloma when there is evidence of bone involvement [124]. The optimal duration and frequency of bisphosphonate therapy for myeloma are not well understood and are currently being studied. All randomized, placebo-controlled tri
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bupropion hydrochloride cost Our two groups of patients were
2019-06-11
Our two groups of patients were similar in all, but two, parameters: the non-inducible group had a significantly higher prevalence of atrial fibrillation (Table 1) and a significantly lower use of β-blockers at the time of enrollment into the study (discharge time after PES only or ICD implantation)
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Several true lumen re entry devices have
2019-06-11
Several true lumen re-entry devices have been introduced into the market, including the Outback catheter, allowing fluoroscopically controlled true arterial lumen re-entry after subintimal guidewire passage. A recent retrospective review reported a successful re-entry rate of 91% in 11 patients with
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Patients with both primary gaze consecutive esotropia Fig
2019-06-11
Patients with both primary gaze consecutive esotropia (Fig. 1) and consecutive exotropia (Fig. 2) showed significantly less vertical deviation postoperatively compared with preoperative measurements (p Discussion The treatment of constant vertical tropia associated with consecutive horizontal dev
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