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However as the above results included patients who underwent
2019-04-20
However, as the above results included patients who underwent RMN ablation during its introduction to our center when physicians were still in the process of familiarization, we proceeded to compare fluoroscopy and procedural times in the most recent 50 patients undergoing ablation in each cohort. T
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XL184 Respecto a estos ltimos el Papel Peri dico de la
2019-04-20
Respecto a estos últimos, el Papel Periódico de la ciudad de Santafé de Bogotá (1791-1797) se constituyó en el órgano difusor de las discusiones adelantadas en la tertulia y se afirmó la necesidad de obtener la utilidad común y la contribución a la causa pública. En palabras de Renán Silva: Hasta e
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br Conclusions Implantable monitoring devices have
2019-04-20
Conclusions Implantable monitoring devices have become highly useful diagnostic tools for AT/AF [32]. However, the accuracy of the obtained diagnostic information is influenced by several factors, including the presence of non-AT/AF events, such as RNRVAS or PMT, caused by VA conduction or by sub
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Introduction Personalized medicine is the major goal of
2019-04-20
Introduction Personalized medicine is the major goal of translational research in the post-genomic era. Numerous biomarkers have been identified by genomic or proteomic approach that can reclassify the disease thapsigargin and predict clinical outcome. However, to define a specific disease phenoty
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In order to treat metastatic bone disease effectively all st
2019-04-20
In order to treat metastatic bone disease effectively all steps involved in the metastatic cascade need to be taken into account as for example the interactions between primary and secondary sites, tumour cell–bone cell cross talk and osteomimicri [8]. Therefore, concomitant targeting of both the tu
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Adem s las situaciones en las que Nicol
2019-04-20
Además, las situaciones en las que Nicolás se encuentra con las piedras, sus dudas en torno protease activated receptor si son piedras-huesos o simples piedras, sus caminatas por cerros, encrucijadas y pueblos más o menos fantasmales, las respuestas diferentes a sus preguntas por Pedro Páramo (“¿se
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Mechanistic target of rapamycin mTOR a highly conserved seri
2019-04-20
Mechanistic target of rapamycin (mTOR), a highly conserved serine-threonine protein kinase, is a key regulator of cell growth and metabolism. As discussed above, mTORC1 is a negative regulator of the preinitiation complex that modulates the initiation of autophagosome biogenesis. Pharmacological and
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br We welcome the efforts by Robert Cohen and
2019-04-20
We welcome the efforts by Robert Cohen and colleagues to promote country-specific targets for post-2015 health goals. Publications from the Consortium of Universities for Global Health () conference included a welcome focus on the building of effective global health education programmes. Histor
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br A manera de conclusi n El peri
2019-04-20
A manera de conclusión El periódico La Lucha mantuvo una postura contra la intervención estadounidense en el proceso independentista cubano de 1895. Misma que refrendó en la coyuntura de la imposición de la Enmienda Platt. En esa ocasión utilizó un lenguaje grandilocuente que vislumbraba un futur
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To the best of our
2019-04-19
To the best of our knowledge, only one other group studied low-dose protracted oral clofarabine in MDS patients who failed hypomethylating agents. They studied 5mg (fixed dose) daily for 10 consecutive days of a 28-day cycle. All patients who were treated for 10 days had a greater than 25% drop in t
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br A new model of human
2019-04-19
A new model of human wellbeing is emerging to guide humanity in the Anthropocene. In essence, it recognises that wellbeing depends on enabling every person to lead a life of dignity and opportunity, while safeguarding the integrity of Earth\'s life-supporting systems. The conceptual framework of s
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Ja s et al reported that complete
2019-04-19
Jaïs et al. reported that complete LAVA elimination is a better predictor of success than the absence of inducibility [23]. Achieving complete elimination of LAVA yields superior survival free from recurrent VT during long-term follow-up. Scar homogenization significantly increases the freedom from
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br The UN high level Summit for Refugees and
2019-04-19
The 2016 UN high-level Summit for Refugees and Migrants in New York (NY, USA) provided a historic opportunity to engage world leaders in responding to the health dimensions of mass migration. Despite the magnitude of the phenomenon and its potential for changing global as well as national health p
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RANK RANKL The RANK RANKL signaling pathway is
2019-04-19
RANK/RANKL: The RANK/RANKL signaling pathway is a critical component of both normal and malignant bone remodeling. RANK is a transmembrane signaling receptor and a member of the tumor necrosis receptor (TNF) superfamily that is found on the surface of OCL precursors [43,44]. RANK ligand (RANKL) is e
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Apart from their association with severe pain
2019-04-19
Apart from their association with severe pain and reduced quality of life, SREs require substantial healthcare resource utilization (HRU) in their treatment and management. Previous retrospective studies have attempted to quantify various aspects of the burden of SREs across specific tumor types/cou
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