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br Case report Positron emission
2019-04-29
Case report Positron emission tomography (PET) and computed tomography (CT) revealed a tumor in the upper two-thirds of the esophagus with a maximal length of 14.38 cm and at least 6 enlarged lymph nodes. Complete computer-controlled radiation therapy was performed on June 12, 2015, and a chest C
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The standard therapy for chordoma is excision
2019-04-29
The standard therapy for chordoma is excision. Local recurrence, but not metastasis, is a major determinant of prognosis. Because local recurrence is related to initial surgical margin and intra-operative tumor cell contamination, achieving a safe margin is very important. Boriani [6] reported 153 c
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br We thank Jordi Landier and colleagues for
2019-04-29
We thank Jordi Landier and colleagues for their comments about our recent Article in . In their work, Landier and coworkers generalise some of our observations on Buruli ulcer in Benin to those for Cameroon, the country that has the fifth highest prevalence of Buruli ulcer worldwide. Briefly, they
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The median standardised inclusion score for the countries re
2019-04-29
The median standardised inclusion score for the 70 countries reviewed was 1·53 (IQR 0·63–2·09), corresponding to a reasonable level of inclusion. Countries showing best practice (score of 4) were Moldova, Ghana, Serbia, and the Dominican Republic. 20 countries (29%) showed strong inclusion, 25 count
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galanin La reivindicaci n del m
2019-04-29
La reivindicación del mártir revolucionario El proceso del egp dio lugar galanin consolidar un frente de estudiantes constituido con su línea política, trabajo continuo del estudiantado identificado con ello; respecto a la dirección de esta organización, carecemos de comunicados o publicaciones que
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Editorial opinion piece Many patients with advanced
2019-04-28
Editorial/opinion piece Many patients with advanced cancer will develop bone metastases and associated complications, including severe pain and debilitating skeletal-related events (SREs), which require radiotherapy, surgery or changes to antineoplastic regimens [1–3]. Fortunately, there are effect
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These data indicate that typhoid
2019-04-28
These data indicate that typhoid is a substantial disease burden in many parts of Africa, with the incidence levels likely to be an underestimate because of the difficulty of estimating true levels on the basis of microbial culture. The report has encouraged the funding of TSAP to be continued for a
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br Introduction Percutaneous transcatheter device closure of
2019-04-28
Introduction Percutaneous transcatheter device closure of atrial septal defects (ASD) has become an effective alternative therapy to surgical repair in patients with secundum type ASD. Amplatzer ASD or ventricular septal defect (VSD) occluders were used for the closure of ASDs or VSDs, respective
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br CaMKII and heart failure progression CaMKII is a multifun
2019-04-28
CaMKII and heart failure progression CaMKII is a multifunctional serine–threonine kinase, phosphorylating target proteins. Under resting conditions, CaMKII is inactive. A rise in intracellular Ca2+ stimulates binding of Ca2+ to calmodulin (CaM), a ubiquitous Ca2+-binding protein. The Ca2+/CaM com
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Letsas et al reported that the prevalence of Brugada
2019-04-28
Letsas et al. reported that the prevalence of Brugada-type ECG was 0.34% in men and 0.04% in women in the Greek population [19]. Despite the similar BS gender differences between the Greeks and the Japanese, many multicenter studies performed in Western countries indicated that the frequency of men
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br Conclusion br Conflict of
2019-04-28
Conclusion Conflict of interest Introduction Dermatofibrosarcoma protuberans (DFSP) is a rare soft-tissue neoplasm that was first identified by Taylor, RW in 1890. It was then described in 1924 by Darier, J and Ferrand, M as a progressive recurrent dermatofibroma, and was later termed DFSP
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br Radiotherapy for bone metastases As a
2019-04-28
Radiotherapy for bone metastases As a palliative intervention, radiotherapy is effective and efficient at treating painful bone metastases, and the side effects associated with its use are manageable and usually self-limiting in nature. Between 50% and 80% of patients gain at least partial relief
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Whole body CT only showed mild splenomegaly cm
2019-04-28
Whole-body CT only showed mild splenomegaly (14cm) and an enlarged iliac lymph node (1.5×3cm). Cranial MR yielded no specific findings. In the meantime, the patient was given Rituximab. He received 375mg/m2 of Rituximab per week, but after the third dose the patient rapidly developed shock and abdo
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Adenosine is an important factor to participate the generati
2019-04-26
Adenosine is an important factor to participate the generation of ATP. What’s more, adenosine has significant endogenous protective effect such as suppressing the release of excitatory amino acid, reducing the permeability of cell membrane to calcium ion, expanding blood vessel of brain, preventing
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purchase Digoxigenin-11-dUTP T wave alternans is a periodic
2019-04-26
T-wave alternans is a periodic beat-to-beat variation in the amplitude or morphology of the T wave on electrocardiography (ECG) (Fig. 1). Beat-to-beat T-wave alternans is considered to reflect increased dispersion of ventricular repolarization, and it is known to often precede the development of let
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